Chicken Alfredo Casserole Recipe

Stacey Mebs | Bake.Eat.Repeat. Updated

This Chicken Alfredo Casserole with a healthier homemade Alfredo sauce makes the perfect weeknight meal - easy to make and everyone loves it!

My family absolutely loves pasta (as most probably do), so everyone is happy when I make this Chicken Alfredo Casserole for dinner.

Chicken Alfredo Casserole Photo

It's the perfect choice for a weeknight meal. It's super easy to make, comes together quickly, and everyone loves it.

Plus, there's usually some leftovers, so that's a few less lunches to make the next day. Which always makes me happy.

Chicken Alfredo Casserole Picture

The only problem comes when there's not enough for everyone and we have to fight over the leftovers.

This recipe will be in the regular dinner rotation for a very long time I think!

What is Alfredo sauce made of?

This Chicken Alfredo Casserole uses a lightened up homemade Alfredo sauce. It's made with milk, butter, garlic, and parmesan cheese, with thyme, oregano, salt, and pepper for seasoning.

It's super easy to make and is ready in less time than it takes to boil the penne.

Chicken Alfredo Casserole Image

I would highly recommend making the sauce instead of buying a bottle of pre-made Alfredo sauce, although that's always an option if you want super easy dinner prep. 

Can you use milk instead of heavy cream for Alfredo sauce?

Using milk instead of heavy cream for this light Alfredo sauce is the main difference.

You need to add some flour to thicken it up, but it's a significant reduction in fat and calories to make it with milk instead of cream. And the flavour is still fantastic.

In all honesty, I probably choose this light version over the real thing 90% of the time - mostly because I always have milk, but not cream, sitting in the fridge. Also, it's just healthier!

Chicken Alfredo Casserole Pic

What goes well with Alfredo sauce?

We absolutely love the combination of penne, chicken, and broccoli with Alfredo sauce. But feel free to change it up a bit if you like. 

Any pasta shape will work just fine here, so use what you have on hand. I do prefer smaller shaped pasta instead of long pasta like fettuccine for this recipe though.

You can also change up the protein and vegetable if you like to whatever you have on hand.

File 1 - Chicken Alfredo Casserole

How to make Chicken Alfredo Casserole:

  • This recipe mixes up very quickly, but it does call for cooked chicken. If you don't have any on hand, you can easily make it earlier in the day with this Crockpot Shredded Chicken recipe. Or make it while you're cooking your penne and making the Alfredo sauce with this Instant Pot Shredded Chicken recipe.
     
  • I like using a lightened up Alfredo sauce for this recipe, but feel free to change it up and use the real thing. Here is the Homemade Alfredo Sauce recipe I like. For this Chicken Alfredo Casserole you will need a double recipe of that sauce. It makes about a 1/2 cup more sauce then is called for here so you may not need it all if you go that route.
     
  • This makes a 9x13 inch pan of pasta, and easily feeds my family of five with leftovers for at least a couple of people for lunch the next day. 

Here are some more great pasta recipes for you:

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Chicken Alfredo Casserole Recipe

    6 Servings

Ingredients

  • 12 ounces Penne
  • 4 tablespoons Unsalted Butter
  • 4 cloves Garlic, minced
  • 1/4 cup All-Purpose Flour
  • 3 1/2 cups Milk, (I used 2%)
  • 1 teaspoon Dried Thyme
  • 1 teaspoon Dried Oregano
  • 1/2 teaspoon Salt
  • 1/2 teaspoon Black Pepper
  • 1 cup Shredded Parmesan Cheese, divided
  • 4 cups Cooked Shredded Chicken
  • 3 cups Broccoli Florets, (small)
  • 2 cups Shredded Mozzarella Cheese

Directions

  1. Preheat the oven to 350°F.
  2. Cook the penne according to the package directions in a large pot of boiling water. Drain.
  3. Meanwhile, in a medium saucepan, over medium heat, melt the butter.
  4. Add the garlic and cook, stirring, for about 30 seconds, until fragrant.
  5. Whisk in the flour, and cook, whisking constantly, until it is lightly browned, about 1 minute.
  6. Slowly whisk in the milk, stirring until it is incorporated and smooth.
  7. Add the thyme, oregano, salt, pepper, and 1/2 cup of the parmesan cheese, and whisk continuously for 3-4 minutes, or until the sauce has thickened slightly.
  8. Reduce the heat to a low simmer until the pasta is ready.
  9. Toss together the cooked penne, chicken, broccoli, and Alfredo sauce, and transfer everything to a 9x13 inch baking dish.
  10. Sprinkle the mozzarella cheese, and the remaining 1/2 cup parmesan cheese on top of the pasta.
  11. Bake for 20-25 minutes, or until the cheese is melted and bubbling.

 

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Cooking Method:
Baked
Category:
Casseroles
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Related Recipes:
Casserole Recipes, Chicken Casserole Recipes, Easy Dinner Recipes, Easy Recipes, Pasta Recipes, Chicken Recipes, Broccoli Recipes, Sauce Recipes, Baked Recipes
Recipe Yields:
6 servings
Prep Time:
Cook Time:
Total Time:
Related Post:
Published:
Author: Stacey Mebs
Recipe Yields: 6 servings
Prep Time: 20 minutes
Cook Time: 20 minutes
Total Time: 40 minutes

Nutrition Facts

Servings Per Recipe 6

Amount Per Serving
Calories from Fat 200
Calories 768

% Daily Value*
39%
Total Fat 25g
70%
  Saturated Fat 14g
45%
Sodium 1090mg
21%
Total Carbohydrate 62g
4%
  Dietary Fiber 3g
  Sugars 8g
117%
Protein 58g

* Percent Daily Value are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
** Nutrition Facts are estimated based on ingredients and data provided by Fat Secret. Please consult a doctor if you have special dietary needs.
Stacey Mebs

About Stacey

Stacey loves to Bake. Eat. Repeat. so much that it inspired the name of her blog. With three young kids at home, she's become an expert at packing lunches. Say hello to our Lunchbox fanatic!