In a medium saucepan, over medium-low heat, combine butter, olive oil, garlic powder, oregano, and pepper. Heat until butter is melted.
Meanwhile, in a large bowl, combine parsley and oyster crackers. Pour melted butter mixture over crackers and parsley. Toss to combine until crackers are fully coated with butter.
Spread on a rimmed sheet pan, sprinkle with Romano cheese and toss gently to combine. Spread them out so they are in a single layer.
Bake for 15 minutes, stir gently (return back to a single layer) and bake for 10 more minutes or until golden brown.
Let cool completely before storing in an airtight container (but they taste best fresh!).
Keyword Appetizers, Baked, Baking, Easy, Family Meals and Snacks, Party Food, Snacks